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Job Description

Job Title:

Scientist – Cell-based Bioassays

Summary:

Employed as a Scientist responsible for cell-based assay research, and experimentation for the purposes of new method development, validation, and sample analysis. Responsible for consulting with clients on drug discovery or development needs and establishing appropriate assays or products to meet client need.

Job Duties:

Responsible for day to day activities for cell-based Laboratory
Consult with PI, Chief Scientific Officer regarding research, and prepare experimental design, scientific articles, technical papers and reports.
Collaborate with PIs/ Chief Scientific Officer to research grant topics and write grants.
Develop and validate cell-based assays to characterize biosimilar products and establish bio comparability with innovator products.
Develop and validate cell-based assays to detect neutralizing antibodies in biological matrices
Develop and validate Ligand binding assays to characterize the receptor binding properties of biotherapeutics and their biosimilars
Design and execute experiments, analyze and interpret experimental results contributing to research program strategies
Responsible for troubleshooting problems with bioassay methods that may arise.
Prepares standards and specifications for processes, products, and tests.
Oversees proper maintenance, qualification and day-to-day user logging of equipment usage in the lab
Coordinate technology/methods transfer to external collaborators and contract research organizations
Assure scientific quality and client service targets are achieved.
Maintain professional and technical knowledge by attending educational workshops; reviewing Skills/Qualifications:

Requirements:

PhD in Biological Sciences (Immunology, Cell Biology or related field)
Minimum 10 years’ experience in assay development or equivalent combination of education and experience.
In depth experience in Cell-based bioassays. The intended purpose of the assay to assess the mechanism of action (MOA) and potency of biologics. Our different cell-based assay platforms include: Enzymatic/reporter-based assays, CDC, ADCC, potency, proliferation, migration, inhibition and cytotoxicity etc.
Experience in protein biochemistry (protein purification, Western blotting, Immunoprecipitation, etc.)
Ability to work within an interdisciplinary team environment with internal and external team members
Strong project management and decision making skills
Ability to write read and interpret technical and scientific reports and correspondence.
Ability to schedule and arrange own activities to accomplish them.
Must be independent and creative thinker with ability to solve complex problems.

If you are interested in being considered for this position:

Email resume to: hr@somrubioscience.com. Please indicate “Scientist – Cell-based Bioassays” on the subject line of your email.